LDN treatment for MS?
Question by sowettt25: LDN treatment for MS?
Is anyone taking LDN for MS? if so did you take it as your first treatment for MS? or did you take it after taking another treatment? Is it good? how effective is it ? does it stop the progression of MS? Is it hard to get LDN? please help .. my big brother has just found out he has MS and will start taking his first avonex shot in 2 days but I have been reading about the LDN treatment I told him about it but he said it is not approved or something… Please help anything to save my big brother from a sad desperate baby sister 🙁
Best answer:
Answer by researchtissue
About Low Dose Naltrexone
What is Low Dose Naltrexone?
Naltrexone is a drug called an opiate antagonist. Used to treat opiate drug addiction, it blocks the response to opiate drugs, such as heroin or morphine. Doses for this are 50-150mg. The idea of using LDN for MS was devised by Dr. Bernard Bihari, a practising neuro-physician in New York, USA. Low-dose Naltrexone (LDN) has been in use in the United States in the treatment of MS since 1985. It is used much less in the UK.
How does it work?
In MS, LDN works by briefly obstructing the effects of brain endorphins (the brain’s natural painkillers). This has an effect of stimulating the increased production of these same endorphins, which in turn stimulate the immune system, thus reducing the activity of the MS.
What MS Symptoms does LDN help?
Neuromuscular spasm and fatigue. Also patients who are in the middle of an acute relapse when they start LDN have generally shown rapid resolution of the attack.
Dose
For MS, 4.5mg each day, taken late each evening. Early research shows that a dose of naltrexone 3mg is able to increase the level of T-cells by 300%. This benefit lasts around 18 hours.
Does it work?
Reports show that 98 to 99% of people with MS on LDN experience no further disease progression in both relapsing-remitting and chronic progressive MS. Dr. Bihari has more than 70 people with MS in his practice and all have been stable over an average of three years. The original patient who used this therapy has been taking the drug for 17 years. In addition, more than 2000 people with MS within the United States, have been prescribed LDN by their own doctors.
Side-effects
At high dose (150mg+) the drug has a number of significant side-effects. At the recommended dose of 3-4.5mg no significant side-effects have been reported. It should be noted that this treatment cannot be used by those people already receiving beta interferon. Because LDN stimulates the immune system and beta interferon suppresses it, the two therapies are incompatible.
How soon does it work?
Around two-thirds have some symptomatic improvement within the first few days.
Where to get LDN?
Contact MSRC for the latest information updates. Please note the MSRC DO NOT sell LDN, but can put you in touch with those that do – please see the article below from Bob Lawrence, for up to date supply and costing details
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